Progeria in popular Media and Culture:
Charles Dickens has been suggested in Bleak House to have described a case of progeria in the family of Smallweed in the grandfather and his grandchildren Judy and twin brother Bart.
The 1922 short story "The Curious Case of Benjamin Button" by F. Scott Fitzgerald (and later released as a feature film in 2008) may have been inspired by progeria. The main character, Benjamin Button, is born as a seventy-year-old man and ages backwards.
The Hindi film "Paa", released in December 2009, has its story line around progeria (starring Amitabh Bachchan playing a thirteen year old boy Auro).
Leon Botha, a South African visual artist and DJ who appeared in a video for the conceptual rave-rap group Die Antwoord, is one of the oldest people in the world living with Progeria Syndrome.
Progeria was featured in the X-Files episode "Young at Heart," where a scientist studying the disease found a way to reverse the aging process.
Rabbi Harold Kushner, author of the well known book, "When Bad Things Happen to Good People", had a son who suffered from this disease, and likely his son's tragic illness was the impetus for this book on suffering.
In the film Blade Runner the character J.F.Sebastian is a genetic designer who is not allowed to emigrate off-world because of his progeria.
Progeria is also a central theme in the animated film "Renaissance" in which one of the characters finds the much sought cure.
Orlando Gardiner of the science fiction book series Otherland suffers from this disorder.
The Chuck Palahniuk novel Haunted includes one character, Brandon Whittier, who is dying of progeria at 13.
On the episode "Designate This" from the series "Dark Angel", Max's "younger version" has the disease.